Regulatory
Part:BBa_K2272001:Design
Designed by: Eric Joshua Wang Group: iGEM17_Virginia (2017-10-21)
promoter MnSOD
Assembly Compatibility:
- 10COMPATIBLE WITH RFC[10]
- 12COMPATIBLE WITH RFC[12]
- 21COMPATIBLE WITH RFC[21]
- 23COMPATIBLE WITH RFC[23]
- 25COMPATIBLE WITH RFC[25]
- 1000COMPATIBLE WITH RFC[1000]
Design Notes
As pMnSOD is only 133 b.p. in length, a denser gel should be used to perform gel electrophoresis for this promoter. In our case, we used Nusieve agarose gel for pMnSOD.
Source
Hypoxic modulation of manganese superoxide dismutase promoter activity and gene expression in lung epithelial cells. https://www.ncbi.nlm.nih.gov/pubmed/10385600
MnSOD in Oxidative Stress Response-Potential Regulation via Mitochondrial Protein Influx. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3942709/#B127